Fat-busting medicine in tests for heart benefits.

Doctors in Perth, Autralia will be testing a brand newmechanism of how this pill functions and the part it
weight-loss pill in the hope it will not only help them losecould play in fat people who have various risk
weight but also cut their chance of heart diseases byingredients for heart conditions, one of which is low
increasing levels of good cholesterol or HDL. TheHDL cholesterol, or metabolic syndrome, he said.
hospital trials, as part of an international trials, couldProfessor Watts said the bottom line is to help people
prove the weight-loss drug called Zimulti, developed bylose weight, which in turn reduces their chance of
the French drugmaker Aventis, can preclude theother diseases such as diabetes. It means that people
condition known as metabolic syndrome, a particularlyend up eating less and burning more fat so its a very
high risk form of weight gain which entails problemshefty tool for targeting obesity, but beyond that its also
controlling cholesterol, insulin and blood pressure. Geraldan hefty tool for helping smoking and even alcohol
Watts, RPH professor of medicine, who specialises inabuse, he said. The hospital is enroling men and
metabolic disorders, said the pill is expected to bewomen between 35 and 65 who are overweight or
approved in Australia within a few months and theobese with a waist circumference of more than
hospital aimed to enroll 15 to 20 patients as part of the40inches in men and 88cm in women and have high
80 being studied worldwide. The medications that havetriglycerides with low HDL cholesterol. They will be put
been available until now have had toxic consequenceson a diet to lose 5 per cent of their body weight and
and some work but have no long-term safety data, sosome will be selected to continue on the Zimulti trials. In
this is a new approach to the controlling of weight gain.trials that have been done, the gains that have been
The pill works by blocking chemical processes in theseen in terms of increasing HDL cholesterol could not
brain, which results in less craving and also acts on thebe excused by the loss of weight alone, so it clearly
liver to help the body melt more fat, but side-effectshas a direct consequence on the good cholesterol.
can include nausea and diarrhea. Were curious in the